It also shifts melanin production from the darker eumelanin toward the lighter pheomelanin, which is why it is used for skin brightening
Endocrinology 144 , 37993810 (2003)
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[7] Once researchers recognized that the N-terminal 29 residues carried the full GH-releasing activity, sermorelin (GRF 129) became the natural first clinical tool
[7] [8] This observation led to the identification of GLP-1 as one of the key incretin hormones responsible for this enhanced insulin response
These include: Transient fever Redness, itching, and rashes Dry mouth Sensitivity at the site of injection Nausea Headaches However, based on the findings of long-term research involving exogenous GH therapy (not ipamorelin, specifically) we can see that elevated GH levels have been linked to severe side effects, including: Researchers interested in running clinical trials with ipamorelin would be well-advised to exclude test subjects pre-existing conditions such as hypertension or diabetes